Surgical Treatment of Pulmonary Aspergillosis (III).
- Author:
Sung Chol JUNG
1
;
Woo Shik KIM
;
Yun Suk BAE
;
Hwan Kook YOO
;
Seung Hyuck CHUNG
;
Jung Ho LEE
;
Byung Yul KIM
Author Information
1. Department of Thoracic & Cardiovascular Surgery, National Medical Center, Korea. ice-bar@hanmail.net
- Publication Type:Original Article
- Keywords:
Aspergilloma, pulmonary;
Lung surgery
- MeSH:
Aspergillosis;
Aspergillus;
Asphyxia;
Bronchial Arteries;
Colon;
Empyema;
Fungi;
Hemoptysis;
Hemorrhage;
Humans;
Immunodiffusion;
Incidence;
Lung;
Lung Diseases;
Mortality;
Postoperative Complications;
Pulmonary Aspergillosis*;
Retrospective Studies;
Sex Ratio;
Sputum;
Thorax;
Tuberculosis;
Tuberculosis, Pulmonary
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2003;36(7):497-503
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Pulmonary aspergillosis usually results from the colonization of the existing lung lesions by chronic pulmonary diseases, such as tuberculosis. Most cases of pulmonary aspergilloma have been treated surgically for many years because it is a potentially life-threatening disease causing massive hemoptysis. Here we reviewed our results from the last 10 years. MATERIAL AND METHOD: We reviewed 31 cases surgically treated from Aug. 1992 to Jul. 2002. retrospectively. This investigation is designed to illustrate the peak age incidence, sex ratio, chief complaints, preoperative study, anatomic location of operative site, postoperative pathologic finding and postoperative complications. RESULT: The peak age incidence laid in the 3rd and 4th decade of 20 cases (64.5%). The most common complaint was hemoptysis in 27 cases (87.1%). The 31 cases had a history of treatment with anti- tuberculous drugs under impression of pulmonary tuberculosis. The 19 cases (61.3%) showed the so-called "Air- meniscus sign" on the preoperative chest X-ray. In the 31 cases (100%) on the chest computed tomography. as a preoperative diagnostic modality, positivity was shown in 37.9%, 83.3% was shown on the fungus culture of sputum for Aspergillus, serum immunodiffusion test for A. fumigatus, respectively. The anatomical location of aspergilloma was mainly in the upper lobe in 19 cases (61.3%) and the majority of cases were managed by lobectomy. The postoperative pathologic findings showed that 31 cases (100%) were combined with tuberculosis. The postoperative complications include empyema, prolonged air leakage, remained dead space, postoperative bleeding and these numbers of cases is 3 cases (9.7%), 2 cases (6.45%), 2 cases (6.45%), 1 case (3.23%), respectively. one case was died postoperatively due to massive beeding, and asphyxia. CONCLUSION: Compared with the previous study, there is no significant difference in results. Preoperative chest computed tomography and immunodiffusion test were more commonly available and showed high positivity. Operations often became technically difficult because of pleural space obliteration, indurated hilar structures, and poor expansion of the remaining lung, which were more prominent in the patients with complex aspergillosis. In such cases, medical treatments and interventional procedures like bronchial artery embolization are preferred. However, cavernostomy is also recommanded with few additional morbidity because of its relatively less invassiveness. Early surgical intervention is the recommended management for patients with simple aspergilloma considering the low surgical mortality and morbidity in recent days.
