Outcome of total proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis.
10.4174/jkss.2012.83.3.135
- Author:
Wontae CHO
1
;
Yong Beom CHO
;
Jin Yong KIM
;
Dong Kyung CHANG
;
Young Ho KIM
;
Hee Cheol KIM
;
Seong Hyeon YUN
;
Woo Yong LEE
;
Ho Kyung CHUN
Author Information
1. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. gscyb@skku.edu
- Publication Type:Original Article
- Keywords:
Ulcerative colitis;
Proctocolectomy;
Complications
- MeSH:
Colitis, Ulcerative;
Fistula;
Follow-Up Studies;
Humans;
Ileitis;
Interviews as Topic;
Intraabdominal Infections;
Nutritional Support;
Pouchitis;
Risk Factors;
Serum Albumin;
Ulcer
- From:Journal of the Korean Surgical Society
2012;83(3):135-140
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We evaluated the risk factors for late complications and functional outcome after total proctocolectomy (TPC) with ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC). METHODS: Pre- and postoperative clinical status and follow-up data were obtained for 55 patients who underwent TPC with IPAA between 1999 and 2010. The median follow-up duration was 4.17 years. Late complications were defined as those that appeared at least one month after surgery. For a functional assessment, telephone interviews were conducted using the Global Assessment of Functioning Scale. Twenty-eight patients completed the interview. RESULTS: Late complications were found in 20 cases (36.3%), comprising pouchitis (n = 8), bowel obstruction (n = 5), ileitis (n = 3), pouch associated fistula (n = 2), and intra-abdominal infection (n = 2). The preoperative serum albumin level for patients with late complications was lower than for patients without (2.4 +/- 0.5 vs. 2.9 +/- 0.7, P = 0.04). Functional outcomes were not significantly associated with clinical characteristics, follow-up duration, operation indication, or late complications. CONCLUSION: This study demonstrated that a low preoperative albumin level could be a risk factor for late complications of TPC with IPAA. Preoperative nutritional support, especially albumin, could reduce late complications. Functional outcomes are not related to late complications.
