Central Hypoventilation Syndrome during Awake and Sleep.
- Author:
Hye Sik KIM
1
;
Seong Min PARK
;
Si Ryung HAN
;
Yeong In KIM
Author Information
1. Department of Neurology, College of Medicine, The Catholic University of Korea.
- Publication Type:Original Article
- Keywords:
Central hypoventilation syndrome;
Respiratory center;
Pyramidal tracts;
Magnetic resonance imaging
- MeSH:
Brain;
Cerebral Cortex;
Humans;
Hypoventilation*;
Magnetic Resonance Imaging;
Neurologic Manifestations;
Paresis;
Primary Dysautonomias;
Pyramidal Tracts;
Quadriplegia;
Respiratory Center;
Respiratory Insufficiency;
Respiratory System
- From:Journal of the Korean Neurological Association
2000;18(5):645-649
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Central hypoventilation syndrome (CHS) can be caused by any lesions to the medullary respiratory centers, cerebral cortex, corticospinal pathways, and their connections. We report 5 patients with central hypoventilation syndrome and analyzed 26 patients who experienced central hypoventilation syndrome during sleep and waking states. We compared initial clinical symptoms and signs, maximal neurologic deficits, brain MRI and pathologic findings, and associated autonomic dysfunctions. The patients with respiratory failure during waking states showed quadriplegia, a rapidly progressing respiratory failure. The patients who had automatic respiratory failure showed mild hemiparesis, bulbar dysfunction, dysautonomia, and subacute to chronic recurrent respiratory failures. These results support the concept of two separate respiratory systems: a voluntary system and an automatic system. The respiratory management of these patients with central hypoventilation syndrome should be considered critical to their survival.