A Case of Breast Cancer Brain Metastasis with a 16-Year Time Interval without Evidence of Cancer Recurrence.
10.4048/jbc.2017.20.2.212
- Author:
Shoko Merrit YAMADA
1
;
Yusuke TOMITA
;
Soichiro SHIBUI
;
Takashi KUROKAWA
;
Yasuhisa BABA
Author Information
1. Department of Neurosurgery, Teikyo University Mizonokuchi Hospital, Kawasaki, Japan. merrityamada@hotmail.co.jp
- Publication Type:Case Report
- Keywords:
Brain;
Breast neoplasms;
Local neoplasm recurrence;
Prognosis
- MeSH:
Adenocarcinoma;
Aged;
Brain*;
Breast Neoplasms*;
Breast*;
Cerebellar Ataxia;
Diagnosis;
Drug Therapy;
Female;
Humans;
Magnetic Resonance Imaging;
Neoplasm Metastasis*;
Neoplasm Recurrence, Local;
Prognosis;
Recurrence*;
Whole Body Imaging
- From:Journal of Breast Cancer
2017;20(2):212-216
- CountryRepublic of Korea
- Language:English
-
Abstract:
The median time of brain metastasis from the diagnosis of breast cancer is approximately 3 years. In this case report, a 69-year-old woman demonstrated cerebellar ataxia. Brain magnetic resonance imaging revealed enhanced lesions in bilateral cerebellar hemispheres. She had undergone surgery, radiation, and chemotherapy for uterine and breast cancer 24 years prior and 16 years prior, respectively. Although she had not received any anticancer treatment for 10 years, no recurrences were identified using whole body scans. A partial tumor resection was performed and the histological diagnosis was an adenocarcinoma from breast cancer. As no extracranial lesions were found, gamma-knife irradiation was performed, without additional systemic chemotherapy. One month posttreatment, the tumors dramatically reduced in size and the patient completely recovered from cerebellar ataxia. Systemic chemotherapy is not always required for brain metastasis from breast cancer with a long interval period, as long as no evidence of extracranial recurrence is detected.