Helicobacter apodemus sp. nov., a new Helicobacter species identified from the gastrointestinal tract of striped field mice in Korea.
10.4142/jvs.2015.16.4.475
- Author:
Woo Jin JEON
1
;
Hee Jin DONG
;
Jae Hoon SHIN
;
Il Yong KIM
;
Hungwui HO
;
Seung Hyun OH
;
Young Min YOON
;
Yang Kyu CHOI
;
Jun Gyo SUH
;
Ki Hoan NAM
;
Hyoung Chin KIM
;
Seongbeom CHO
;
Je Kyung SEONG
Author Information
1. Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BIO-MAX Institute, Program for Cancer Biology, and Interdisciplinary Program for Bioinformatics, BK21Plus Program for Creative Veterinary Science Research, Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea. snumouse@snu.ac.kr
- Publication Type:Original Article
- Keywords:
16S rRNA;
Apodemus agrarius;
Helicobacter apodemus;
striped field mouse
- MeSH:
Animals;
Catalase;
Cephalothin;
Databases, Nucleic Acid;
Flagella;
Gastrointestinal Tract*;
Genes, rRNA;
Helicobacter*;
Korea*;
Mice*;
Microscopy, Electron;
Murinae*;
Nalidixic Acid;
Oxidoreductases;
Sequence Analysis;
Urease
- From:Journal of Veterinary Science
2015;16(4):475-481
- CountryRepublic of Korea
- Language:English
-
Abstract:
A novel Helicobacter species was identified from the gastrointestinal tract of the Korean striped field mouse (Apodemus agrarius). Biochemical testing, ultrastructure characterization, and 16S rRNA gene sequence analysis suggested that this bacterium represents a distinct taxon. The bacterium was positive for urease activity, susceptible to cephalothin and nalidixic acid, and weakly positive for oxidase and catalase activity. Electron microscopy revealed that the bacterium has spirally curved rod morphology with singular bipolar nonsheathed flagella. Genotypically, the isolated bacterial strains (YMRC 000215, YMRC 000216, and YMRC 000419) were most closely related to a reference strain of Helicobacter mesocricetorum (97.25%, 97.32%, and 97.03% 16S rRNA sequence similarities, respectively). The 16S rRNA sequences of these strains were deposited into GenBank under accession numbers AF284754, AY009129, and AY009130, respectively. We propose the name Helicobacter apodemus for this novel species.
