The Transient Syndrome of Headache with Neurologic Deficits and CSF Lymphocytosis.
- Author:
Sang Jin KIM
1
;
Kyoung HEO
;
Jong Hwan KIM
;
Oeung Kyu KIM
;
Sung Eun KIM
Author Information
1. Department of Neurology, Pusan Paik Hospital, Inje University College of Medicine.
- Publication Type:Original Article
- MeSH:
Adult;
Aphasia;
Extremities;
Female;
Fever;
Headache*;
Hemianopsia;
Humans;
Hypesthesia;
Lymphocytosis*;
Migraine Disorders;
Neurologic Manifestations*;
Paresis;
Spinal Puncture
- From:Journal of the Korean Neurological Association
1998;16(3):398-401
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In 1981, Bartleson et al described seven patients who experienced three to 12 episodes of headache accompanied by neurologic deficits and CSF lymphocytosis. The headache pain was severe and of a type not previously experienced by the patients. The neurologic deficits were temporary, usually lasting hours and at most 3 days. The CSF showed a predominantly lymphocytosis and increased protein. We report a patients of this syndrome. A 39 year-old woman without a history of migraine developed a right-sided severe headache with weakness in the right extremities. Three days earlier she had an upper respiratory infection. At admission she had a fever. Her speech was dysarthric. She had left homonymous hemianopsia, left-sided hemiparesis and hypoesthesia. Lumbar puncture revealed 180 WBCs (90% lymphocytes) and total protein 132 mg/dl. The symptoms and signs cleared completely within 18 hours. Three days later, she experienced left-sided severe headache followed 1 hour later by confusion after cerebral angiogram. Her language showed Wernicke's aphasia. A repeat lumbar puncture revealed similar result to first attack. The symptoms again cleared two days later. She has remained free of symptoms for 28 months. This syndrome is a self-limited condition, but the etiology of this syndrome is unknown. The monophasic nature and a high frequency of an associated fever and viral illness favor infectious origin.
