Perfusion MR Imaging: Clinical Utility for the Differential Diagnosis of Various Brain Tumors.
- Author:
Sung Ki CHO
1
;
Dong Gyu NA
;
Jae Wook RYOO
;
Hong Gee ROH
;
Chan Hong MOON
;
Hong Sik BYUN
;
Jong Hyun KIM
Author Information
- Publication Type:Original Article
- Keywords: Brain neoplasms, diagnosis; Brain neoplasms, diagnosis; Brain, perfusion; Magnetic resonance (MR), perfusion study
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Blood Volume/physiology; Brain/*pathology/physiopathology; Brain Neoplasms/*pathology/physiopathology/secondary; Diagnosis, Differential; Female; Human; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Middle Age; Time Factors
- From:Korean Journal of Radiology 2002;3(3):171-179
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: To determine the utility of perfusion MR imaging in the differential diagnosis of brain tumors. MATERIALS AND METHODS: Fifty-seven patients with pathologically proven brain tumors (21 high-grade gliomas, 8 low-grade gliomas, 8 lymphomas, 6 hemangioblastomas, 7 metastases, and 7 various other tumors) were included in this study. Relative cerebral blood volume (rCBV) and time-to-peak (TTP) ratios were quantitatively analyzed and the rCBV grade of each tumor was also visually assessed on an rCBV map. RESULTS: The highest rCBV ratios were seen in hemangioblastomas, followed by high-grade gliomas, metastases, low-grade gliomas, and lymphomas. There was no significant difference in TTP ratios between each tumor group (p<0.05). At visual assessment, rCBV was high in 17 (81%) of 21 high-grade gliomas and in 4 (50%) of 8 low-grade gliomas. Hemangioblastomas showed the highest rCBV and lymphomas the lowest. CONCLUSION: Perfusion MR imaging may be helpful in the differentiation of thevarious solid tumors found in the brain, and in assessing the grade of the various glial tumors occurring there.
