Status Epilepticus Induced by Respiratory Syncytial Virus Infection in Preterm Infants.
- Author:
Min Hee JEONG
1
;
Eun Hye LEE
;
Mi Sun YUM
;
Tae Sung KO
Author Information
1. Department of Pediatrics, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea. tsko@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Respiratory syncytial viruses;
Infant;
Premature;
Seizures;
Status epilepticus
- MeSH:
Child;
Electroencephalography;
Humans;
Infant;
Infant, Newborn;
Infant, Premature;
Midazolam;
Neurologic Manifestations;
Phenobarbital;
Phenytoin;
Respiratory Syncytial Viruses;
Seizures;
Status Epilepticus
- From:Journal of Korean Epilepsy Society
2009;13(2):75-78
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Respiratory syncytial virus (RSV) is an extremely common cause of childhood respiratory infection resulting in significant morbidity and mortality especially in young infants and premature babies. There have been a few reports about seizures or encephalopathy in children with RSV infection. We describe here refractory status epilepticus in two preterm babies with severe respiratory illness by RSV infection. The seizures were refractory to phenobarbital and diphenylhydantoin, but ceased by continuous midazolam infusion. After several days with clinical improvement of respiratory illness, their seizures were stable on phenobarbital maintenance only. Although rare, status epilepticus can be a form of neurologic manifestation of severe RSV infection in preterm baby. We must be aware of their neurological manifestations; continuous EEG monitoring is helpful for the diagnosis of the status epilepticus in infants.
