Usefulness of Chromoscopy Using Lugol Solution for Detection of Superficial Esophageal Cancer.
- Author:
Young Il MIN
;
Hae Ryun KIM
;
Hwoon Yong JUNG
;
Suk Kyun YANG
;
Weon Seon HONG
;
Hyun Sook KIM
;
Hyo Jung KIM
;
Do Ha KIM
- Publication Type:Original Article
- Keywords:
Chromoscopy;
Lugol staining;
Superficial esophageal cancer;
Smoking
- MeSH:
Chungcheongnam-do;
Delayed Diagnosis;
Epithelial Cells;
Esophageal Neoplasms*;
Glycogen;
Humans;
Korea;
Prognosis;
Prospective Studies;
Smoke;
Smoking;
Survival Rate
- From:Korean Journal of Gastrointestinal Endoscopy
1996;16(6):921-927
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Background/Aims: Esophageal cancer is not an uncommon cancer in Korea, however, the prognosis still remains very poor with a 5 year survival rate bemg less than l0% mainly becauae of the delayed diagnosis. Although chromoscopy with lugol solution has been received to diagnose the esophageal cancer in an early stage without difficulty, its clinical use has not been popular yet in Korea. This study was performed prospectively to evaluate the usefulness of the chromoscopy for the detection of superficial esophageal cancer in risk patients for esophageal cancer. Methods: Ninety-five patients were selected among persons who received gasiroscopy at Asan Medical Center between Jan. 1996 and May 1996 and were prospectively included for chromoscopy. Inclusion criteria for the chromoscopy were patients older than 60 years of age with smoking history of more than 30 packyears, and/or past or family history of cancers. After conventional endoscopic examination, lugol solution was sprayed to stain the glycogen granules in the epithelial cells. The size of unstained lesion was measured and stainability was classified into 5 grades. All lesions unstained were biopsied for histological diagnosis.(continue...)
