Emergent Carotid Stenting in Acute Stroke Patients With Steno-Occlusion of Proximal Internal Carotid Artery.
- Author:
Gi Youn BAE
1
;
Jeong Ho HONG
;
Sung Il SOHN
;
Chul Ho SOHN
;
Hyuk Won CHANG
Author Information
1. Department of Neurology, Keimyung University School of Medicine, Daegu, Korea. docsohn@dsmc.or.kr
- Publication Type:Original Article
- Keywords:
Endovascular therapy;
Stent;
Internal carotid artery;
Acute stroke
- MeSH:
Carotid Arteries;
Carotid Artery, Internal;
Constriction, Pathologic;
Humans;
National Institutes of Health (U.S.);
Risk Factors;
Smoke;
Smoking;
Stents;
Stroke;
Weights and Measures
- From:Journal of the Korean Neurological Association
2008;26(3):177-185
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The aim of this study was to investigate the feasibility and efficacy of emergent carotid artery stenting (CAS) for occlusion or high-grade stenosis of the internal carotid artery (ICA) in patients with acute ischemic stroke. METHODS: From November 2004 to May 2007, 17 patients admitted to the hospital within 12 hours of symptom onset with occlusion or a high-grade stenosis of the proximal ICA underwent emergent CAS. We analyzed risk factors, imaging findings, functional outcome scales, and peri-procedural complication. The outcome was measured by the modified Rankin scale (mRS) 3 months later and classified into good (mRS score of 0 to 2) or poor (mRS score of 3 to 6). RESULTS: All patients were recanalized successfully. The median National Institutes of Health Stroke Scale (NIHSS) score was 12.6 (range 4 to 24) just before the emergent CAS, which decreased to 9.4 and 8.2 at 1 day and 7 days after the stenting. Three months later, 12 patients showed good outcome while three had poor outcome and two of them died. Two patients (11.8%) exhibited symptomatic hemorrhagic transformation following the emergent CAS. Smoking status, and initial and immediate post-procedural NIHSS scores were associated with the outcome. CONCLUSIONS: Emergent CAS is a feasible and effective method in acute treatment of selected stroke patients with steno-occlusion of the proximal ICA.