A case of central pontine myelinolysis in uremic patient with peritoneal dialysis.
- Author:
Seung Hoon LEE
1
;
Ho Cheol SONG
;
Hyung Jun KIM
;
Hyeon Jae KIM
;
Sun Mi PARK
;
Won Jong YU
;
Euy Jin CHOI
;
Byung Ki BANG
Author Information
1. Departments of Internal Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Myelinolysis, Central pontine;
Sodium;
Continuous ambulatory peritoneal dialysis;
Magnetic resonance imaging
- MeSH:
Aged;
Blood Glucose;
Brain;
Diabetic Coma;
Dialysis;
Fasting;
Female;
Humans;
Hyponatremia;
Magnetic Resonance Imaging;
Myelinolysis, Central Pontine*;
Osmolar Concentration;
Peritoneal Dialysis*;
Peritoneal Dialysis, Continuous Ambulatory;
Pons;
Renal Dialysis;
Sodium
- From:Korean Journal of Medicine
2001;61(6):660-663
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Central pontine myelinolysis (CPM) is a rare syndrome, especially in uremic patients undergoing dialysis. CPM induced by diabetic coma in hemodialysis patients or associated with rapid correction of hyponatremia in peritoneal dialysis patients have been reported. However, its pathogenesis has been unclear. We report a case of CPM in a 67-year-old female uremic patient undergoing continuous ambulatory peritoneal dialysis, who was admitted to our hospital for drowsy mentality. Sodium was normal (140 mEq/L) initially and throughout the entire clinical course. The fasting blood sugar level was 110 mg/dL, serum osmolality 312 mOsm/KgH2O and osmolar gap 9.47. The axial T2-weighted brain MRI showed high signal intensity in the basal pons.
