Cigarette Smoking and Mortality in the Korean Multi-center Cancer Cohort (KMCC) Study.
10.3961/jpmph.2010.43.2.151
- Author:
Eun Ha LEE
1
;
Sue K PARK
;
Kwang Pil KO
;
In Seong CHO
;
Soung Hoon CHANG
;
Hai Rim SHIN
;
Daehee KANG
;
Keun Young YOO
Author Information
1. Department of Preventive Medicine, Seoul National University College of Medicine, Korea. kyyoo@snu.ac.kr
- Publication Type:Original Article ; Multicenter Study
- Keywords:
Cigarette smoking;
Cohort studies;
Mortality
- MeSH:
Aged;
Cohort Studies;
Female;
Health Behavior;
Humans;
Life Style;
Male;
Middle Aged;
Neoplasms/mortality;
Proportional Hazards Models;
Republic of Korea/epidemiology;
Smoking/*mortality
- From:Journal of Preventive Medicine and Public Health
2010;43(2):151-158
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: The aim of this study was to evaluate the association between cigarette smoking and total mortality, cancer mortality and other disease mortalities in Korean adults. METHODS: A total of 14 161 subjects of the Korean Multi-center Cancer Cohort who were over 40 years of age and who were cancer-free at baseline enrollment reported their lifestyle factors, including the smoking status. The median follow-up time was 6.6 years. During the follow-up period from 1993 to 2005, we identified 1159 cases of mortality, including 260 cancer mortality cases with a total of 91 987 person-years, by the national death certificate. Cox proportional hazard regression model was used to estimate the hazard ratio (HR) of cigarette smoking for total mortality, cancer mortality and disease-specific mortality, as adjusted for age, gender, the geographic area and year of enrollment, the alcohol consumption status, the education level and the body mass index (BMI). RESULTS: Cigarette smoking was significantly associated with an increased risk of total mortality, all-cancer mortality and lung cancer mortality (p-trend, <0.01, <0.01, <0.01, respectively). Compared to non-smoking, current smokers were at a higher risk for mortality [HR (95% CI)=1.3 (1.1-1.5) for total mortality; HR (95% CI)=1.6 (1.1-2.2) for all-cancer mortality; HR (95% CI)=3.9 (1.9-7.7) for lung cancer mortality]. CONCLUSIONS: This study's results suggest that cigarette smoking might be associated with total mortality, all-cancer mortality and especially lung cancer mortality among Korean adults.
