Splenic Littoral Cell Angioma with Hepatitis C Associated Liver Cirrhosis.
10.4174/jkss.2010.78.3.203
- Author:
Young Wha KOH
1
;
Bong Hee PARK
;
Sang Ryung LEE
;
Heejin LEE
;
Joo Ryung HUH
Author Information
1. Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. jrhuh@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Littoral cell angioma;
Spleen;
Cirrhosis;
Hepatitis C
- MeSH:
Adult;
Ascites;
Esophageal and Gastric Varices;
Female;
Fibrosis;
Hemangioma;
Hepatitis;
Hepatitis C;
Humans;
Incidental Findings;
Korea;
Liver;
Liver Cirrhosis;
Liver Transplantation;
Spleen;
Splenectomy;
Splenic Neoplasms;
Vascular Neoplasms
- From:Journal of the Korean Surgical Society
2010;78(3):203-206
- CountryRepublic of Korea
- Language:English
-
Abstract:
Littoral cell angioma (LCA) of spleen is an uncommon vascular neoplasm of littoral cell origin. It is well established that LCA may be associated with other malignancy or autoimmune disorders. We describe a 34-year-old woman with viral hepatitis C associated liver cirrhosis who presented with the incidental finding of LCA. She showed ascites, esophageal varix and drowsy mentality. Abdominal computed tomography (CT) showed multiple benign looking nodules in both hepatic lobes, but no abnormality in spleen. Liver transplantation and splenectomy were performed. Microscopic findings revealed narrow anastomosing vascular channels lined with plump cells that exfoliated into the lumen. Immunohistochemically the lining cells were positive for CD31, CD68 and negative for CD34, consistent with LCA. Herein, a second case of an incidentally detected LCA with cirrhosis, viral hepatitis C associated in Korea is reported.
