The Distribution of Fetal Nuchal Translucency Thickness in Normal Korean Fetuses.
10.3346/jkms.2004.19.1.32
- Author:
Jin Hoon CHUNG
1
;
Jae Hyug YANG
;
Mi Jin SONG
;
Jeong Yeon CHO
;
Young Ho LEE
;
So Yeon PARK
;
Myoung Jin MOON
;
Ha Jung LIM
;
June Seek CHOI
;
Joo Oh KIM
;
Joong Sik SHIN
;
Hyun Kyong AHN
;
Jung Yul HAN
;
Moon Young KIM
;
Kyu Hong CHOI
;
Hyun Mee RYU
Author Information
1. Department of Obstetrics and Gynecology, Samsung Cheil Hospital and Women's Healthcare Center, Sungkyunkwan University, School of Medicine, Seoul, Korea. ryu97@samsung.co.kr
- Publication Type:Original Article
- Keywords:
Nuchal Translucency;
Pregnancy Trimester, First;
Crown-rump Length;
Ultrasonography
- MeSH:
Adult;
Chromosome Aberrations;
Crown-Rump Length;
Female;
Fetus/*physiology;
*Gestational Age;
Human;
Korea;
Linear Models;
Pregnancy;
Pregnancy Trimester, First;
Pregnancy Trimester, Second;
Ultrasonics;
Ultrasonography, Prenatal
- From:Journal of Korean Medical Science
2004;19(1):32-36
- CountryRepublic of Korea
- Language:English
-
Abstract:
The aim of present study was to establish normative data for the distribution of nuchal translucency (NT) thickness in normal Korean fetuses. The data were collected from pregnant women with singleton pregnancies in whom fetal ultrasound was performed and the fetal NT thickness was measured between 11 and 14 weeks of gestation. Among them, a total of 2,577 fetuses with a known normal outcome were included in this study. The distribution of multiple of median (MoM) values of the NT thickness with crown-rump length (CRL) in 10-mm intervals and the 95th percentile of MoM were calculated with the linear regression method. The present study showed that NT measurements increase with increasing CRL and a false positive rate increases with increasing gestational age. Therefore, a fixed cut-off point through the first trimester was not appropriate and each NT measurement should be examined according to the gestational age. The present study offers normative data of the fetal NT thickness in a Korean population, which can be used as reference for screening chromosomal aberrations or other congenital abnormalities in the first trimester.
