Therapeutic Strategies of the Intracranial Meningioma in Elderly Patients.
10.3340/jkns.2007.41.4.217
- Author:
Young Jin SONG
1
;
Soon Ki SUNG
;
Seung Jin NOH
;
Hyung Dong KIM
Author Information
1. Department of Neurosurgery, Dong-A University College of Medicine, Busan, Korea. hdkim@donga.ac.kr
- Publication Type:Original Article
- Keywords:
Intracranial meningioma;
CRGS;
Elderly patients;
Prognosis
- MeSH:
Aged*;
Decision Making;
Edema;
Humans;
Incidence;
Meningioma*;
Postoperative Complications;
Prognosis;
Retrospective Studies
- From:Journal of Korean Neurosurgical Society
2007;41(4):217-223
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: The apparent increase in the incidence of the intracranial meningiomas in the elderly is due in part to improved diagnostic tools and improved span of life. The authors carried out a retrospective study to validate the use of the Clinical-Radiological Grading System (CRGS) as a clinical tool to orientate surgical decision making in elderly patients and to explore prognostic factors of survival. METHODS: From January 1997 to January 2006, the authors consecutively recruited and surgically treated 20 patients older than 65 years of age with radiologic findings of intracranial meningiomas and a preoperative evaluation based on the CRGS. RESULTS: High CRGS score was associated with a higher probability of good outcome (p=0.004) and a lower probability of postoperative complications (p=0.049). Among the different subset items of the CRGS score, larger maximum tumor diameters (D> or =4cm) and the presence of a severe peritumoral edema were associated with incidence rate of postoperative poor outcome and complications (p<0.05). Additionally, the critical location of the tumor was also correlated with poor outcome (p<0.05). CONCLUSION: A CRGS score higher than 13 is a good prognostic indication of survival. The CRGS score is a useful and practical tool for the selection of elderly patients affected by intracranial meningiomas as surgical candidates.
