A Study on Viral Hepatitis Markers and Abnormal Liver Function Test in Adults Living in Northwest Area of Chungnam.
10.4166/kjg.2009.53.6.355
- Author:
Suk Bae KIM
1
;
Won Kyung LEE
;
Hoon CHOI
;
So Mi KIM
;
Rhan NOH
;
Ha Yan KANG
;
Sang Suk LEE
;
Sung Soo RA
;
Jae Hwan GONG
;
Hyun Duk SHIN
Author Information
1. Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea. sm1213@paran.com
- Publication Type:Original Article ; English Abstract
- Keywords:
Prevalence;
HBsAg;
Anti-HCV;
Abnormal LFT
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Child;
Female;
Hepatitis B Antibodies/blood;
Hepatitis B Surface Antigens/blood;
Hepatitis B, Chronic/*epidemiology/immunology/physiopathology;
Hepatitis C Antibodies/blood;
Hepatitis C, Chronic/*epidemiology/immunology/physiopathology;
Humans;
Korea;
Liver Function Tests;
Male;
Middle Aged;
Prevalence;
RNA, Viral/blood;
Retrospective Studies
- From:The Korean Journal of Gastroenterology
2009;53(6):355-360
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: We studied the prevalence of chronic hepatitis B, C and abnormality on liver function among the population in northwest area of Chungnam. METHODS: We have reviewed 40,112 adults who had received medical examination at health promotion center in Dankook university hospital. We studied them retrospectively about HBsAg, HBsAb, anti-HCV, and liver function test (LFT). RESULTS: Among the study subjects, 22,936 men and 17,176 women were involved. The overall seroprevalence of HBsAg was 4.2%. The prevalence in men (4.5%) was higher than that of women (3.7%) (p<0.001). The seroprevalence of HBsAg in their age was 5.1% in the 5th decade, 4.2% in the 2nd decade, 4.1% in the 4th decade, and 4.1% in the 6th decade. The overall seroprevalence of HBsAb was 65.1%. The overall seroprevalence of anti-HCV was 0.7%. After we reexamined them with HCV RNA or RIBA (Recombinant Immunoblot Assay), the prevalence of chronic hepatitis C was 0.09%. The LFT abnormality in total subjects was 11.4%. The LFT abnormality of chronic hepatitis B and C subjects was 21.72% and 63.2%. CONCLUSIONS: The prevalence of chronic hepatitis B and C was lower than that of previous studies. The prevalence of chronic hepatitis B in the 2nd decade was still high.
