A Case of Langerhans Cell Histiocytosis in an Adult.
10.5021/ad.1996.8.1.25
- Author:
Woo Kwon JUNG
;
Young Keun KIM
;
Kuy Wang WHANG
;
Hong Kyu LEE
;
Hee Suk PARK
;
Jong Ho WON
- Publication Type:Case Report
- Keywords:
Langerhans cell histiocytosis;
Old age;
Lymph nodes
- MeSH:
Adult*;
Aged;
Dermis;
Histiocytes;
Histiocytosis, Langerhans-Cell*;
Humans;
Immunohistochemistry;
Langerhans Cells;
Lymph Nodes;
Pelvis;
S100 Proteins;
Skin
- From:Annals of Dermatology
1996;8(1):25-29
- CountryRepublic of Korea
- Language:English
-
Abstract:
Langerhans sell bistiocytosis(LCH) is a reactive disease in which abnomal Langerhans cells accurnulate in various body sites and cause damage to affected organs. LCH usually occurs in childrea bur can also affect adults although rarely. LCH in a case of 65-year-old man initially involwed the lymph nodes (left supraclacicular and right inguinal area) and pelvis bone, and eight months later curancous involvement was noted. The skin lesions were waxy from the waxy papules showed that the dense infiltrate, ptedominantly of histiocytes, was present in the dermis, Immunohistochemistry for S-100 protein showed positive staining snd electron miscoroscopy disclosed Birbeck granules, which is characteristic findings of Langerhans cells.
