The role of CA 72-4 in the diagnosis and the monitoring of gastric cancer
- Author:
Son Van Hoang
- Publication Type:Journal Article
- Keywords:
gastric cancer
- MeSH:
Diagnosis;
Stomach Neoplasms;
neoplasms
- From:Journal of Medical and Pharmaceutical Information
2000;(4):29-31
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The tumor marker CA 72-4 has been determined sera of gastric cancer patients to evaluate its role in the diagnosis and the monitoring of treatment. Adenocarcinoma of the stomach: 68 (38 men, 30 women; age 17-70) Gastric ulcer and gastritis: 10 (male: 8, female: 2; age 30-72). Criteria of diagnosis: cytologic examination. 40 patients have been monitored CA 72-4 during one month after operation. There were high statistical difference of CA 71-4 concentrations between cancer and healthy groups (p< 0.001); but no difference between ulcer and healthy people (p<0.005) has been found. The specificity of CA 72-4 for gastric cancer was 100%; sensitivity: 73.53%; Positive predictive value: 100%; Negative predictive value: 35.7%. 77.5% of cases had decreased levels of CA 72-4 after surgery. But in 4 cases, the increased concentrations of this marker correlated with residual tumor. The results showed that CA 72-4 proved to be specific and sensitive in the diagnosis and prognosis and monitoring of surgical treatment of gastric cancer.
