Enhanced compatibility and initial stability of Ti6Al4V alloy orthodontic miniscrews subjected to anodization, cyclic precalcification, and heat treatment.
10.4041/kjod.2014.44.5.246
- Author:
Eun Ju OH
1
;
Thuy Duong T NGUYEN
;
Seung Youp LEE
;
Young Mi JEON
;
Tae Sung BAE
;
Jong Gee KIM
Author Information
1. Sun Dental Hospital, Daejeon, Korea.
- Publication Type:Original Article
- Keywords:
Orthodontic mini-implant;
Stability;
Biocompatibility;
Surface treatment
- MeSH:
Alloys*;
Body Fluids;
Hot Temperature*;
Hydrophobic and Hydrophilic Interactions;
Immersion;
Osseointegration;
Rats, Wistar;
Tibia;
Torque
- From:The Korean Journal of Orthodontics
2014;44(5):246-253
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To evaluate the bioactivity, and the biomechanical and bone-regenerative properties of Ti6Al4V miniscrews subjected to anodization, cyclic precalcification, and heat treatment (APH treatment) and their potential clinical use. METHODS: The surfaces of Ti6Al4V alloys were modified by APH treatment. Bioactivity was assessed after immersion in simulated body fluid for 3 days. The hydrophilicity and the roughness of APH-treated surfaces were compared with those of untreated (UT) and anodized and heat-treated (AH) samples. For in vivo tests, 32 miniscrews (16 UT and 16 APH) were inserted into 16 Wistar rats, one UT and one APH-treated miniscrew in either tibia. The miniscrews were extracted after 3 and 6 weeks and their osseointegration (n = 8 for each time point and group) was investigated by surface and histological analyses and removal torque measurements. RESULTS: APH treatment formed a dense surface array of nanotubular TiO2 layer covered with a compact apatite-like film. APH-treated samples showed better bioactivity and biocompatibility compared with UT and AH samples. In vivo, APH-treated miniscrews showed higher removal torque and bone-to-implant contact than did UT miniscrews, after both 3 and 6 weeks (p < 0.05). Also, early deposition of densely mineralized bone around APH-treated miniscrews was observed, implying good bonding to the treated surface. CONCLUSIONS: APH treatment enhanced the bioactivity, and the biomechanical and bone regenerative properties of the Ti6Al4V alloy miniscrews. The enhanced initial stability afforded should be valuable in orthodontic applications.
