Two Cases of Chlorpromazine-induced Corneal and Lenticular Opacity.
- Author:
Hyung Soo KIM
1
;
Hyun Jung CHOI
;
Young Soo YUN
Author Information
1. Department of Ophthalmology, Pochun CHA University College of Medicine, Pundang CHA Hospital, Sungnam, Korea. hjchoi90@hanmail.net
- Publication Type:Case Report
- Keywords:
Chlorpromazine;
Cornea;
Lens;
Opacity
- MeSH:
Anterior Chamber;
Chlorpromazine;
Conjunctiva;
Cornea;
Humans;
Lens Implantation, Intraocular;
Retina
- From:Journal of the Korean Ophthalmological Society
2002;43(11):2349-2353
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report two cases of corneal deposits and anterior capsular opacity after prolonged chlorpromazine therapy METHODS: Two schizophrenic patients using chlorpromazine showed the corneal endothelial opacity and anterior capsular opacity. They complained of deterioration of vision. And one of them was operated for lenticular opacity by extracapsular lens extraction and posterior chamber intraocular lens implantation. CONCLUSIONS: Because chlorpromazine may induce pigmentary deposits in the conjunctiva, cornea, lens, anterior chamber angle and retina, regular ophthalmic examination seems to be necessary in patients under chlorpromazine therapy.