Laparoscopic biopsy-proven lupus nephritis in autosomal dominant polycystic kidney disease.
- Author:
Ji In PARK
1
;
Hajeong LEE
;
Jung Nam AN
;
Ho Jun CHIN
;
Suhnggwon KIM
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. mednep@snubh.org
- Publication Type:Case Report
- Keywords:
Laparoscopy;
Lupus nephritis;
Polycystic kidney disease
- MeSH:
Arthralgia;
Biopsy;
Cyclophosphamide;
Edema;
Female;
Glomerulonephritis;
Humans;
Laparoscopy;
Lupus Erythematosus, Systemic;
Lupus Nephritis;
Middle Aged;
Polycystic Kidney Diseases;
Polycystic Kidney, Autosomal Dominant;
Proteinuria;
Renal Dialysis;
Serologic Tests;
Steroids;
World Health Organization
- From:Kidney Research and Clinical Practice
2012;31(3):192-195
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 48-year-old woman with autosomal dominant polycystic kidney disease (ADPKD) presented with generalized edema and arthralgia. She showed evidences of acute glomerulonephritis including nephrotic-ranged proteinuria. Because her serologic test results were consistent with those for systemic lupus erythematosus (SLE), we performed laparoscopic renal biopsy that confirmed World Health Organization (WHO) class IV lupus nephritis. She was treated with steroids and intravenous cyclophosphamide pulse therapy and eventually started hemodialysis 8 years after the lupus nephritis was diagnosed. To our knowledge, this is the first case wherein a patient with ADPKD underwent a laparoscopic biopsy for diagnosing lupus nephritis.