A Case of Basal Ganglia Infarct Associated with SLE.
- Author:
Hee Yeong CHEONG
1
;
Hoe Cheol YOON
;
Eun Sook SUH
Author Information
1. Department of Pediatrics, College of Medicine, Soonchunhyang University, Seoul, Korea. essuh@hosp.sch.ac.kr
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Basal ganglia infarct;
Cerebrovascular disease
- MeSH:
Adolescent;
Arthralgia;
Arthritis;
Asian Continental Ancestry Group;
Autoantibodies;
Autoantigens;
Basal Ganglia*;
Central Nervous System;
Child;
Diagnosis;
Exanthema;
Fatigue;
Female;
Fever;
Humans;
Indians, North American;
Infant;
Kidney;
Korea;
Lupus Erythematosus, Systemic;
Male;
Prevalence;
Puberty;
Rheumatic Diseases
- From:
Journal of the Korean Child Neurology Society
2004;12(2):229-234
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic lupus erythematosus(SLE), a rheumatic disease of unknown causes, is characterized by autoantibodies directed against self-antigens, resulting in inflammatory damages to target organs including kidney, blood-forming cells, and central nervous system. The prevalence rates are higher in Native Americans, Asians, Latin Americans and black people. A female to male ratio of approximately 2 : 1 occurs before puberty, and 4 : 1 after puberty. Children of SLE most frequently present with fever, fatigue, arthralgia or arthritis, and rashes. The diagnosis is confirmed by clinical and also laboratory manifestations satisfying at least 4 out of 11 criteria. A central nervous system is not rarely involved in children of SLE with the prevalence rate of 23-44%. However, cerebral infarcts are not a common phenomenon and can be seen only for 6% of children with SLE. There have been no cases reported in Korea. This is why we present a case of basal ganglia infarct associated with SLE in a 19-month old girl. We report this case with a brief review of related literature.
