Isolated Adrenocorticotropic Hormone or Thyrotropin Deficiency Following Mild Traumatic Brain Injury: Three Cases with Long-Term Follow-Up.
10.13004/kjnt.2015.11.2.139
- Author:
Cho Ok BAEK
1
;
Yu Ji KIM
;
Ji Hye KIM
;
Ji Hyun PARK
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea.
- Publication Type:Case Report
- Keywords:
Brain injuries;
Adrenocorticotropic hormone;
Thyrotropin;
Hypopituitarism
- MeSH:
Adrenocorticotropic Hormone*;
Brain Injuries*;
Diagnosis;
Follow-Up Studies*;
Humans;
Hypopituitarism;
Pituitary Hormones;
Thyrotropin*
- From:Korean Journal of Neurotrauma
2015;11(2):139-143
- CountryRepublic of Korea
- Language:English
-
Abstract:
Few studies have examined the clinical features and long-term outcomes of isolated pituitary hormone deficiencies after traumatic brain injury (TBI). Such deficiencies typically present at time intervals after TBI, especially after mild injuries such as concussions, which makes their diagnosis difficult without careful history taking. It is necessary to improve diagnosis and prevent life threatening or morbid conditions such as those that may occur in deficiencies of adrenocorticotropic hormone (ACTH) or thyroid-stimulating hormone (as known as thyrotropin, TSH), the two most important pituitary hormones in hypopituitarism treatment. Here, we report two cases of isolated ACTH deficiency and one case of isolated TSH deficiency. These patients presented at different time points after concussion and underwent long-term follow-ups.
