Intravesical Cidofovir in the Treatment of Hemorrhagic Cystitis after Unrelated Cord Blood Transplantation.
- Author:
Harry YOON
1
;
Jo Eun KIM
;
Ji Soo PARK
;
Jeong Guil LEE
;
Dae Kyu SHIN
;
Doyeun OH
;
So Young CHONG
Author Information
1. Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea. sychong@cha.ac.kr
- Publication Type:Case Report
- Keywords:
Adenovirus;
Cystitis;
Cidofovir;
Cord blood stem cell transplantation
- MeSH:
Adenoviridae;
Adenoviridae Infections;
Cord Blood Stem Cell Transplantation;
Cystitis;
Cytosine;
Fetal Blood;
Hematopoietic Stem Cells;
Hematuria;
Organophosphonates;
Transplants;
Urinary Bladder
- From:Korean Journal of Medicine
2011;81(5):663-666
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hemorrhagic cystitis is a common complication in hematopoietic stem cell transplant recipients. We report a case of hemorrhagic cystitis after unrelated cord blood transplantation associated with adenovirus infection. Despite hydration, hematuria and large clots persisted. We instilled cidofovir into the bladder, which resulted in clearance of the adenovirus and significant clinical improvement. Our case emphasizes the effectiveness of intravesical cidofovir treatment for viral hemorrhagic cystitis.
