DNA Database Searching Using Genetic Relationship.
- Author:
Seung Bum SEO
1
;
Seung Hwan LEE
;
Myun Soo HAN
;
Kyoung Jin SHIN
;
Hwan Young LEE
;
Soong Deok LEE
Author Information
1. Department of Forensic Medicine, Seoul National University College of Medicine, Seoul, Korea. sdlee@snu.ac.kr
- Publication Type:Review
- Keywords:
forensic;
DNA databases;
familial searching
- MeSH:
Alleles;
Criminals;
Databases, Nucleic Acid;
DNA;
Fathers;
Humans;
Korea;
Running;
Siblings
- From:Korean Journal of Legal Medicine
2011;35(2):92-97
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The usefulness of DNA databases is well known. In Korea, many cases have been solved since the establishment of DNA databases in 2010. DNA profiles obtained from criminal evidence are analyzed and are kept in databases, and matching profile is searched. On the matching occasion, DNA databases can provide some investigative information. Close family members, for example father, son or brother, share more alleles than unrelated people. This genetic closeness can be searched using the so called familial searching, and many successful cases have been reported. Management of DNA databases including familial searching needs continuous monitoring and control, especially from ethical view points. Many different views for familial searching have been presented, and each country running DNA databases has their own different policies. We present the utility, approaches and different policies of familial searching as well as arguments for and against familial searching. We also suggest that our appropriate guidelines be mandatory and a proper administrative process be prepared for the start of familial searching.