An Experimental Study on the Passive Transfer of Dermpgaphism.
- Author:
Yoo Shin LEE
;
Seon Hoon KIM
- Publication Type:Original Article
- MeSH:
Humans;
Intradermal Tests;
Skin;
Stroke
- From:Korean Journal of Dermatology
1981;19(1):55-58
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Dermographism is an exaggerated triple response of Lewis and appears as a lineat wheal with a flare at a site in which skin is briskIy stroked with a firm object. The etiology and pathogenesis of dermographism are uncertain but passive transfer tests are sometimes poeitive. The active serum factor has been characteiized as Ig E in some patients. In this experimental study, we tried passive transfer of dermographism with the sera of the patients with dermographism. Twelve dermographic patients' sera were tested to fourteen normal healthy persons and two asymptomatic dermographic persons, total number of thirty nine cases. Only two recipients were passively transferred but they showed positive responses to all sera tested, two and three respectively. This result suggests that not only serum factor but also recipient's factor(s) may be concerned in passive transfer of dermographism.
