Serial Episodes of Gastric and Cecal Perforation in a Patient with Behcet's Disease Involving the Whole Gastrointestinal Tract: A Case Report.
- Author:
Dong Yeob SHIN
1
;
Jae Hee CHEON
;
Jae Jun PARK
;
Hoguen KIM
;
Tae Il KIM
;
Yong Chan LEE
;
Nam Kyu KIM
;
Won Ho KIM
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report ; English Abstract
- Keywords:
Behcet's disease;
Gastrointestinal;
Ulcer;
Perforation;
Hemorrhage
- MeSH:
Behcet Syndrome/complications/*diagnosis/pathology;
Cecal Diseases/complications/pathology;
Diagnosis, Differential;
Endoscopy, Digestive System;
Gastrointestinal Diseases/complications/*diagnosis;
Gastrointestinal Hemorrhage;
Humans;
Intestinal Perforation/*diagnosis/etiology/pathology;
Male;
Middle Aged;
Peptic Ulcer Perforation/pathology;
Stomach Ulcer/complications/pathology
- From:The Korean Journal of Gastroenterology
2009;53(2):106-110
- CountryRepublic of Korea
- Language:English
-
Abstract:
Behcet's disease (BD) has been recognized as multi-systemic chronic vasculitic disorder of recurrent inflammation, characterized by the involvement of multiple organs and resulting in orogenital ulcers, uveitis, and skin lesions. Involvement of the central nervous system, vessels, and intestines in BD often leads to a poor prognosis. Digestive manifestations in BD have been reported in up to 1-60% of cases, although the rate varies in different countries. The most frequent extra-oral sites of gastrointestinal involvement are the ileocecal region and the colon. Gastric or esophageal involvement is reported to be very rare. Moreover, there have been no reports on the simultaneous involvement of the esophagus, stomach, ileum, and colon. Here, we present a 55-year-old Korean man with intestinal BD and multiple ileal and colonic ulcerations complicated by perforation, gastric ulcer with bleeding followed by perforation, and esophageal ulcers with bleeding.