Caspase-3/CPP32 Immunoreactivity and Its Correlation with Frequency of Apoptotic Bodies in Prostate Adenocarcinoma and Benign Prostatic Hyperplasia.
- Author:
Dong Goo KANG
1
;
Nak Gyeu CHOI
Author Information
1. Department of Urology, Hallym University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Apoptosis;
Caspase-3;
Gleason score;
Prostate adenocarcinoma;
BPH
- MeSH:
Adenocarcinoma*;
Apoptosis;
Caspase 3;
Cysteine Proteases;
Genes, Tumor Suppressor;
Neoplasm Grading;
Oncogenes;
Passive Cutaneous Anaphylaxis;
Prostate*;
Prostatic Hyperplasia*
- From:Korean Journal of Urology
2001;42(7):707-712
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Apoptosis is mediated by apoptosis-specific genes, certain oncogenes and tumor suppressor genes. Caspase-3, a group of cysteine proteases, ier in cases with intermediate (Gleason score 5-7) and high-grade (Gleason score 8-10) PCA than cases with BPH and low-grade PCA (Gleason score 2-4).
