A Comparative Study of Endotracheal Aspirates and Protected Specimen Brush in the Quantitative Cultures of the Ventilator-Associated Pneumonia.
10.4046/trd.1995.42.5.737
- Author:
Kyoung Ryeol ROO
1
;
Min Gu KIM
;
Gi Yang KIM
;
Ho Gyeong JUNG
;
Young Ho PARK
;
Byeng Sun KANG
;
Ho Chul KIM
;
Young Sil HWANG
Author Information
1. Department of Internal Medicine, Gyeoungsang National University Collage of Medicine, Chinju, Korea.
- Publication Type:Comparative Study ; Original Article
- Keywords:
Ventilator-associated pneumonia;
Endotracheal aspirate;
Protected brush specimen;
Quantitative cultures
- MeSH:
Diagnosis;
Humans;
Pneumonia;
Pneumonia, Ventilator-Associated*;
Respiration, Artificial
- From:Tuberculosis and Respiratory Diseases
1995;42(5):737-743
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Pneumonia is a frequent complication in patients undergoing mechanical ventilation. Quantitative culture of protected specimen brush(PSB) have shown satisfactory diagnostic accuracy for the diagnosis of ventilator-associated pneumonia. However PSB method is invasive, expensive, and require a bronchoscopic procedure. But endotracheal aspiration(EA) is simple and less expensive. The purpose of our study was to investigate the diagnosic value of EA quantitative cultures. METHOD: We studied 15 cases of ventilator-associated pneumonia(for >72h of mechanical ventilation) patients. Patients were divided into two diagnostic categories. Group I was the patients who were suspicious of clinical pneumonia, Group II was the patients for control. The obtained samples by EA and PSB were homogenized for quantitative culture with a calibrated loop method in all patients. RESULT: Using 103cfu/ml, 105cfu/ml as threshold in quantitative culture of PSB, EA respectively, we found that EA quantitative cultures represented a relatively sentive(70%) and relatively specific (60%) method to diagnose the ventilator-associated pneumonia. CONCLUSION: Although EA quantitative cultures are less specific than PSB for diagnosing ventilator-associated pneumonia. EA quantitative cultures correlated with PSB quantitative culture in patients with clinical pneumonia and may be used to treat these patients when bronchoscopic procedures are not available.
