Fibroadenoma of the Vulva: A Case Report.
- Author:
Hyung Bae MOON
1
;
Hyang Jeong JO
;
Seong Hwan O
;
Gi Youn HONG
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, University of Wonkwang Medical School, Iksan, Korea.
- Publication Type:Case Report
- Keywords:
Vulva;
Fibroadenoma;
Ectopic breast tissue;
Mammary-like glands
- MeSH:
Actins;
Adult;
Breast;
Cytoplasm;
Epithelium;
Estrogens;
Female;
Fibroadenoma*;
Humans;
Muscle, Smooth;
Vulva*
- From:Korean Journal of Obstetrics and Gynecology
2005;48(7):1816-1819
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Fibroadenoma is a rare lesion of the vulva. It has been proposed that the origin of the tissue is either ectopic breast tissue or vulvar mammary-like glands (MLG). We report a case of vulvar fibroadenoma in a 33-year-old woman with a right vulvar mass presenting clinically as vulvar cyst. The cut surface of the tumor showed a white and homogenous appearance that was 2.5 cm in maximum dimension. Microscopically, the lesion was well-circumscribed but non-encapsulated. It revealed nodular, glandular and stromal proliferation, consistent with fibroadenoma of breast. Immunohistochemical staining for the estrogen receptor and progesteron receptor revealed nuclear positivity in the epithelium. Smooth muscle actin confirmed the presence of a myoepithelial cell layer. Staining for pancytokeratin showed epithelial cytoplasmic positivity.