Clinical analysis of synchronous primary neoplasms of the female reproductive tract.
- Author:
Seo Yun TONG
1
;
Yong Sek LEE
;
Jong Sup PARK
;
Jun Mo LEE
;
Seung Eun NAMKOONG
Author Information
1. Department of Obstetrics and Gynecologic, College of Medicine, The Catholic University of Korea, Seoul, Korea. jspark@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Synchronous neoplasm;
Endometrial cancer;
Ovarian cancer;
Prognosis
- MeSH:
Endometrial Neoplasms;
Endometrium;
Female*;
Humans;
Hysterectomy;
Medical Records;
Natural History;
Neoplasms, Multiple Primary;
Ovarian Neoplasms;
Ovary;
Prognosis
- From:Korean Journal of Obstetrics and Gynecology
2006;49(9):1902-1907
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: A histopathologic review of synchronous primary neoplasms of the female reproductive tract was presented and the possible correlation among discrete tumor subsets, natural history, and survival was evaluated. METHODS: Between 2000 and 2005, 20 patients with synchronous primary cancers of the gynecologic malignancy were identified. Clinical and pathologic informations were obtained from medical records. Kaplan-Meier survival analysis was performed. RESULTS: The patients with Synchronous primary malignancies constituted 0.63% of all genital malignancies. The most frequently observed synchronous neoplasms were those of the ovary with the endometrium (40%). The mean age of patient with synchronous ovarian and endometrial cancer was 45.2 years. 8 patients underwent the hysterectomy with bilateral salpingo-oophorectomy and adjuvant therapy. The mean survival is 57 months (SE 10.0, 95% Confidence interval 37-77). CONCLUSION: Synchronous ovarian and endometrial cancers were detected in relatively early age and the prognosis was favorable.