Frosted Branch Angiitis as Ocular Manifestation of Behcet's Disease: Unusual Case Report and Literature Review.
10.3341/kjo.2013.27.6.466
- Author:
Soon Jae KWON
1
;
Dong Ho PARK
;
Jae Pil SHIN
Author Information
1. Department of Ophthalmology, Kyungpook National University School of Medicine, Daegu, Korea. jps11@hanmail.net
- Publication Type:Case Reports ; Review
- Keywords:
Behcet's disease;
Frosted branch angiitis;
Occlusive retinal vasculitis
- MeSH:
Adult;
Behcet Syndrome/*complications/diagnosis;
Diagnosis, Differential;
Fluorescein Angiography;
Fundus Oculi;
Humans;
Magnetic Resonance Imaging;
Male;
Retinal Artery/*pathology;
Retinal Vasculitis/diagnosis/*etiology
- From:Korean Journal of Ophthalmology
2013;27(6):466-469
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report an unusual case of unilateral frosted branch angiitis associated with Behcet's disease, including a review of previously reported cases. A 39-year-old male with history of recurrent oral and genital ulcers presented with visual loss in his left eye. Fundus findings demonstrated occlusive retinal vasculitis resembling acute frosted branch angiitis. Laboratory examinations including viral markers revealed no abnormal findings except positive HLA-B51. The patient was treated with systemic steroid and cyclosporine. Six months after presentation, new oral ulcers and pseudofolliculitis appeared, and he was diagnosed with Behcet's disease following rheumatology consultation. During follow-up, there was no change in visual acuity of hand movement, and disc neovascularization developed even after complete panretinal photocoagulation. Ocular manifestations of Behcet's disease can present as unilateral frosted branch angiitis, and may consecutively involve in both eyes. Early immunosuppressive treatment is recommended.