A case of pachydermoperiostosis with peptic ulcer disease.
- Author:
Jung Lae PARK
1
;
Dong Hyun LEE
;
Jin Ouk KANG
;
Jong Yun CHEONG
;
Hye Kyung PARK
;
Ok Nyu KONG
;
Seok Man SON
;
In Joo KIM
;
Yong Ki KIM
Author Information
1. Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea. regidanggu@hanmail.net
- Publication Type:Case Report
- Keywords:
Pachydermoperiostosis;
Hypertrophic Osteoarthropathy;
Acromegaly;
Peptic Ulcer
- MeSH:
Acromegaly;
Bone Marrow;
Cranial Sutures;
Crohn Disease;
Duodenal Ulcer;
Female;
Fibula;
Fingers;
Foot;
Gastritis;
Hand;
Hemorrhage;
Humans;
Osteoarthropathy, Primary Hypertrophic*;
Osteogenesis;
Peptic Ulcer*;
Periostitis;
Scalp;
Skin;
Stomach Ulcer;
Tibia;
Ulna
- From:Korean Journal of Medicine
2002;63(3):329-334
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We experienced a Korean patient with complete form of pachydermoperiostosis. He presented with typical features consisting of clubbing with spade like enlargement of the hand and feet, thickening of facial skin and scalp, irregular thickening of cortex with periosteal new bone formation involving radii, ulnae, tibiae, and fibulae. Classically, pachydermoperiostosis is characterized by a triad of finger clubbing, periostitis, skin and soft tissue changes, giving an acromegaloid look. A variety of associated abnormalities have been described such as cranial suture defects, female escutcheon, bone marrow failure. There are a few reports documenting gastric ulcer, hypertrophic gastropathy and Crohn's disease as accompanying diseases. The patient had upper gastrointestinal bleeding caused by hemorrhagic gastritis and duodenal ulcer. A case is herein reported of pachydermoperiostosis accompanied by peptic ulcer disease.
