A Case of Kaposi's Sarcoma in a Renal Allograft Recipient.
- Author:
Jong Kyu YANG
;
Sung Wook KIM
;
Seung Churl PAIK
;
Chung Won KIM
;
Suk Young KIM
- Publication Type:Case Report
- Keywords:
Kaposis sarcoma;
Renal transplantation;
Immunosuppression
- MeSH:
Allografts*;
Cyclosporine;
Genetic Predisposition to Disease;
Geography;
Immunosuppression;
Immunosuppressive Agents;
Incidence;
Intestine, Small;
Kidney Transplantation;
Lung;
Lymph Nodes;
Oncogenic Viruses;
Organ Transplantation;
Prednisolone;
Sarcoma;
Sarcoma, Kaposi*;
Skin;
Transplants
- From:Korean Journal of Dermatology
1997;35(3):551-555
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Iatrogenically developed immunosuppression-associated Kaposis sarcoma is the result of immunosuppressive therapy after an organ transplantation, particularly after a renal transplantation. Since the advent of powerful immunosuppressive agents such as cyclosporine, recently the incidence of Kaposis sarcoma has been increased. In addition to immunosuppression, other factors, such as genetic predisposition, environmental and geographic factors, and oncogenic viruses, may play a role in the pathogenesis of this tumor. Ilerein we report a case of Keposis sarcoma with multiple organ involvement of the skin, lung, small intestine and mesenteric lymph node in a renal allograft recipient who received cyclosporine and prednisolone. Reduction of the dosage of immunosuppressant for 1 month resulted in improvement of the cutaneous lesions.
