A Case of Erythema Nodosum-like leukemia cutis.
- Author:
Jong Woo KIM
;
Young Mook YOON
;
Tae Hyung KIM
;
Dong Seok KIM
;
Sang Won KIM
- Publication Type:Case Report
- Keywords:
Acute myelocytic leukemia;
Erythema nodosum-like lesion
- MeSH:
Anorexia;
Antibodies;
Bone Marrow;
Diagnosis;
Drug Therapy;
Erythema*;
Fever;
Humans;
Leukemia*;
Leukemia, Myeloid, Acute;
Male;
Middle Aged;
Skin
- From:Korean Journal of Dermatology
1997;35(3):556-560
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We have encountered a rare case of erythema nodosum-like leukemia cutis associated with acute myelocytic leukemia(AML) in a 57-year-old male. He was in good health until about 2 weeks prior to admission, when the systemic symptoms of high fever, anorexia, general weakness and malaise, and subcutaneous nodules developed. The nodules were multiple, red and noted bilaterally on the pretibial areas. Histological findings of his skin lesions showed diffuse cellular infiltrates intermingled with leukemic cells predominantly involving the adipose tissues. The cells displayed negative stainirig to antibodies CD3 and CD20, but positive staining to LCA. The diagnosis of AML(M4) was made by blood and bone marrow studies. He had a rapid downhill course and was discharged after 2 weeks of admission, with no anti-cancer chemotherapy.