Microscopic Findings of Cultured Human Melanocytes from a Vitiligo Subject.
- Author:
Yang Hoon CHO
;
Mu Hyoung LEE
- Publication Type:Case Report
- Keywords:
Microscopic finding;
Melanocyte;
Vitiligo
- MeSH:
Adult;
Endoplasmic Reticulum, Rough;
Foreskin;
Humans*;
Male;
Melanocytes*;
Skin;
Vitiligo*
- From:Korean Journal of Dermatology
1997;35(3):571-574
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Vitiligo is an acquired systemic disease of the skin characterized by circumscribed patches of complete pigment loss due to destruction of melanocytes. A 28-year old male patient presented with generalized depigmented patchs. We performed microscopic studies of cultured melanocytes from this patient and compared them with those of normal neonatal foreskin. Phase contrast microscopic findings revealed no difference between the two groups of melanocytes, but transmission electron microscopic findings showed dilated circular rough endoplasmic reticulum in cultured melanocytes from our vitiligo patient. We could observe the innate cellular structural aberration of melanocytes from the vitiligo subject.
