Treatment of Blepharospasm with Botulinum A Toxin.
- Author:
Yoon Duck KIM
1
;
Mark R LEVINE
Author Information
1. The Mt. Sinai Medical Center Cleveland, Ohio, USA.
- Publication Type:Original Article
- MeSH:
Blepharospasm*;
Botulinum Toxins, Type A*;
Follow-Up Studies;
Hemifacial Spasm;
Humans;
Spasm
- From:Journal of the Korean Ophthalmological Society
1987;28(3):523-529
- CountryRepublic of Korea
- Language:English
-
Abstract:
Thirty-nine patients with blepharospasm were treated with botulinum A toxin. Twenty-six patients had essential blepharospasm, and thirteen had hemifacial spasm. A total of 113 injections were given, and average follow-up was 14.6 months. The mean preinjection spasm intensity was 2.9+, and the mean post-injection spasm intensity was 0.7+. The mean interval between injections was 4.4 months. The treatment was effective, although transient, in all patients with essential blepharospasm and hemifacial spasm. The toxin had a prolonged effect on the patients who had previously undergone muscle stripping proced ure. The side effects were mild, transient, and local.
