A Case of Systemic Lupus Erythematosus Presenting with Chorea: Evidence for Striatal Hypermetabolism.
- Author:
Sang Won HA
1
;
Sun Ju CHUNG
;
Jae Seung KIM
;
Joo Hyuk IM
;
Myoung Chong LEE
Author Information
1. Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. jhim@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Chorea;
Systemic lupus erythematous (SLE);
Fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET)
- MeSH:
Administration, Oral;
Chorea*;
Female;
Fluorodeoxyglucose F18;
Follow-Up Studies;
Humans;
Lupus Erythematosus, Systemic*;
Metabolism;
Middle Aged;
Putamen
- From:Journal of the Korean Neurological Association
2004;22(3):255-258
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Chorea is an uncommon clinical manifestation of Sytemic lupus erythematosus (SLE). Its pathogenic mechanism has not been clearly clarified. We report a 54-year-old woman with SLE who presented with generalized chorea as an initial manifestation. Fluorine-18-fluorodeoxyglucose (FDG) PET revealed increased metabolism in the bilateral putamen. Intravenous and oral administration of steroid markedly improved chorea. Hypermetabolism of the bilateral putamen diminished on follow-up FDG-PET after the disappearance of chorea. This study suggests that chorea in SLE is associated with striatal hypermetabolism.
