Ataxic Variant of Guillain-Barre Syndrome Associated with Anti-GD1b Ig G Antibody.
- Author:
Jong Seok BAE
1
;
Dong Ju YOON
;
Min Ky KIM
;
Byoung Joon KIM
Author Information
1. Department of Neurology, Kangnam General Hospital Public Corporation, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Guillain-Barre syndrome;
Cerebellar ataxia;
Autoantibody;
Anti GD1b
- MeSH:
Action Potentials;
Cerebellar Ataxia;
Demyelinating Diseases;
Eye Movements;
Guillain-Barre Syndrome*;
Humans;
Immunoglobulin G;
Neural Conduction;
Quadriplegia
- From:Journal of the Korean Neurological Association
2004;22(3):269-271
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
It is known that anti GD1b antibody bind to the cerebellar granular layer or spinocerebellar Ia fiber. We recently encountered a patient of Guillain Barr syndrome (GBS) showing marked cerebellar ataxia and relatively mild quadriparesis but completely intact extraocular eye movement. Markedly high IgG anti GD1b antibody titer was identified from the patient's serum. The nerve conduction study showed reduction of compound muscle action potential without evidence of perpheral nerve demyelination. We report an ataxic variat of GBS associated with anti GD1b IgG antibody.
