Anti-Hu Antibody Associated Sensory Neuronopathy Accompanied by Autonomic Dysfunction.
- Author:
Young Eun PARK
1
;
Hwan JOO
;
Dae Seong KIM
;
Dae Soo JUNG
;
Kyu Hyun PARK
;
Min Ki LEE
Author Information
1. Department of Neurology, Pusan National College of Medicine, University, Korea. dskim@pusan.ac.kr
- Publication Type:Case Report
- Keywords:
Paraneoplastic polyneuropathy;
Autonomic nervous system;
Small cell carcinoma
- MeSH:
Autonomic Nervous System;
Brachiocephalic Veins;
Carcinoma, Small Cell;
Female;
Humans;
Hypohidrosis;
Middle Aged;
Paraneoplastic Polyneuropathy;
Polyneuropathies;
Small Cell Lung Carcinoma;
Syncope;
Thorax
- From:Journal of the Korean Neurological Association
2004;22(3):272-275
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Paraneoplastic sensory neuronopathy may present with autonomic dysfunction resulting either from autonomic neuropathy, or invasion/compression by tumor. We present a 61-year-old female presented with frequent syncope, anhidrosis, and sensory change. Investigations disclosed sensory-autonomic polyneuropathy with positive anti-Hu antibody. The chest computed tomography showed a left mediastinal mass with invasion to the brachiocephalic vein, and a small cell lung cancer was confirmed. She was treated with radiation therapy showing limited improvement. The possible causes of autonomic dysfunction in our patient were discussed.
