A Meta-Analysis of the Effects of Exercise Programs on Glucose and Lipid Metabolism and Cardiac Function in Patients with TypeII Diabetes Mellitus.
10.4040/jkan.2005.35.3.546
- Author:
Ji Soo YOO
1
;
Suk Jeong LEE
Author Information
1. College of Nursing, Yonsei University, Korea.
- Publication Type:Original Article ; English Abstract ; Meta-Analysis ; Review
- Keywords:
Meta-Analysis;
Exercise;
Diabetes mellitus;
Glucolysis;
Lipolysis
- MeSH:
Oxygen Consumption;
Middle Aged;
Male;
Lipids/*blood;
Humans;
Hemoglobin A, Glycosylated/analysis;
Hemodynamic Processes;
Female;
*Exercise;
Diabetes Mellitus, Type 2/*metabolism/physiopathology/therapy;
Blood Glucose/*analysis
- From:
Journal of Korean Academy of Nursing
2005;35(3):546-554
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was a systematic review and meta-analysis of the effects of exercise programs in patients with type II diabetes mellitus. METHOD: Two investigators systematically searched and reviewed English articles from PUBMED from 1988 to 2004, selecting randomized controlled trials on structured exercise programs for DM patients. Out of 87 studies identified, a meta analysis was done for eleven studies which satisfied inclusion criteria and focused on glycemic indices, lipid indices, and cardiac function indices. RESULTS: The means and standard deviations were compared for experimental groups that received exercise-only or exercise and diet programs and control groups that received no intervention or only diet education. The groups were considered homogeneous as the p value of the Q score in each variable group was over 0.05. The experimental groups demonstrated a moderate positive effect on HbA1c and VO2max (d=0.55 & 0.5), and a small positive effect on fasting blood glucose and cholesterol (d=0.38 & 0.27) compared to the control groups. HDL and LDL cholesterol levels, however, showed a very low positive effect (d=0.11 & 0.12) in the experimental groups. Aerobic exercise was more beneficial than resistance exercise on HbA1c (d=0.59 vs 0.28) in the groups. CONCLUSIONS: Regular exercise has a positive effect on HbA1c, fasting blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, and VO2max in Type 2 diabetic patients.
