Contrast-Enhanced Magnetic Resonance Angiography for Evaluation of the Steno-occlusive Disease of the Supraaortic Arteries: Comparison with Computed Tomography Angiography and Digital Subtraction Angiography.
- Author:
Su Kyung JEH
1
;
Bum Soo KIM
;
So Lyung JUNG
;
Kook Jin AHN
;
Yong Sam SHIN
;
Kwan Sung LEE
;
Young In KIM
;
Kwang Soo LEE
Author Information
1. Department of Radiology, St.Mary Hospital, The Catholic University of Korea, Korea.
- Publication Type:Original Article
- Keywords:
Diagnostic accuracy;
Sensitivity and specificity;
Contrast enhanced MR angiography
- MeSH:
Angiography;
Angiography, Digital Subtraction;
Constriction, Pathologic;
Female;
Humans;
Magnetic Resonance Angiography;
Magnetic Resonance Spectroscopy;
Magnetics;
Magnets;
Male;
Mass Screening;
Retrospective Studies;
Sensitivity and Specificity
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2009;13(2):152-160
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To intra-individually compare diagnostic accuracy of high-resolution contrast-enhanced magnetic resonance angiography (CE-MRA) with computed tomography angiography (CTA) and digital subtraction angiography (DSA) for the assessment of supraaortic steno-occlusive disease. MATERIALS AND METHODS: Twenty-eight patients (20 men, 8 women, 53-79 years of age) underwent supraaortic CE-MRA, CTA and DSA. CE-MRA was performed on two 1.5T MR scanners (voxel dimension: 0.66x0.66x1.1 or 1.2 mm3), and CTA on 64-slice CT scanners (voxel dimension: 0.42x0.42x0.63 mm3). All the three examinations were completed within 40 days (median 19 days; range 1-40 days). Retrospective evaluation and measurement of diameter of 6 extracranial and 9 intracranial arterial segments was done by 2 experienced radiologists. RESULTS: A total of 420 arterial segments were examined by CE-MRA, CTA and DSA. On DSA, 34 stenoocclusive lesions were noted at extracranial (n=19) and intracranial (n=15) vessels. For extracranial stenosis greater than 70%, sensitivity, specificity, positive predictive value (PPV) and negative predictive values (NPV) were 94.7%, 98.7%, 90.0% and 99.3% on CE-MRA, and 94.7%, 99.3%, 94.7% and 99.3% on CTA. For intracranial stenosis greater than 50%, sensitivity, specificity, PPV and NPV were 93.3%, 98.3%, 77.8%and 99.6% on CE-MRA, and 86.7%, 97.9%, 72.2% and 99.1% on CTA, with DSA as the standard of reference. CONCLUSION: Supraaortic CE-MRA is as reliable as CTA in depicting the arterial stenosis, and is effective in screening of significant stenosis of both extracranial and intracranial arterial stenosis.
