Pulmonary Hypertension Associated with Use of Phentermine.
10.3349/ymj.2010.51.6.971
- Author:
Woo Dae BANG
1
;
Ji Ye KIM
;
Hee Tae YU
;
Sung Soo CHO
;
Ji Yong JANG
;
Chang Myung OH
;
Boyoung JOUNG
;
Hyuk Jae CHANG
Author Information
1. Cardiology Division, Yonsei Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea. hjchang@yuhs.ac
- Publication Type:Case Reports
- Keywords:
Phentermine;
pulmonary hypertension
- MeSH:
Adult;
Antihypertensive Agents/therapeutic use;
Electrocardiography/methods;
Female;
Humans;
Hypertension, Pulmonary/*drug therapy/*etiology;
Models, Chemical;
Obesity/drug therapy;
Phentermine/*adverse effects/*therapeutic use;
Radiography, Thoracic/methods;
Safety;
Sulfonamides/therapeutic use
- From:Yonsei Medical Journal
2010;51(6):971-973
- CountryRepublic of Korea
- Language:English
-
Abstract:
Weight-control drugs (known as anorexigens) such as fenfluramine have been linked with pulmonary hypertension in previous reports. In our case, a 29 year old woman was admitted for shortness of breath and was diagnosed with pulmonary hypertension. Three months ago, she had been taking phentermine for five weeks. Other factors that might have contributed to the development of pulmonary hypertension were excluded. With treatment, her symptoms improved. This is the first case that can suggest a possible connection between phenermine single medication with pulmonary hypertension. Phentermine has been considered a relatively safe drug to treat obesity, and further investigation is needed to decide the safety and dosage of phentermine.
