A Case of Recurrent Squamous Cell Carcinoma Showing Perineural Invasion of the Facial Nerve.
- Author:
Ji Woong KIM
1
;
Jeong Eun KIM
;
Soo Hong SEO
;
Sang Wook SON
;
Il Hwan KIM
Author Information
1. Department of Dermatology, Korea University College of Medicine, Seoul, Korea. kumcihk@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Perineural invasion;
Recurrent squamous cell carcinoma
- MeSH:
Carcinoma, Squamous Cell;
Facial Nerve;
Humans;
Immunosuppression;
Lymph Nodes;
Neoplasm Metastasis;
Parotid Gland;
Risk Factors
- From:Korean Journal of Dermatology
2008;46(3):352-354
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The high-risk factors of cutaneous squamous cell carcinoma (cSCC) include size (>2 cm), thickness/depth of invasion (>4 mm), recurrent lesions, the presence of perineural invasion (PNI), location near the parotid gland, and immunosuppression. These patients have a higher risk (>10~20%) of developing metastases to regional lymph nodes based both on unfavorable primary lesions and also patient factors. Among the risk factors, the PNI is often underappreciated by clinicians and is not well documented in the literature. But it is also important that clinicians treating cSCC have an understanding and awareness of PNI. We report a case of recurrent squamous cell carcinoma showing PNI of the facial nerve and review current concepts of PNI.
