Cutaneous Metastasis of Papillary Thyroid Carcinoma: Iatrogenic Cause?.
- Author:
Chan Ho NA
1
;
Sang Hyun SONG
;
Min Sung KIM
;
Bong Seok SHIN
Author Information
1. Department of Dermatology, Chosun University Medical School, Gwangju, Korea. derm75@chosun.ac.kr
- Publication Type:Case Report
- Keywords:
Cutaneous metastasis;
Iatrogenic;
Papillay thyoid carcinoma
- MeSH:
Biopsy;
Biopsy, Fine-Needle;
Carcinoma;
Dermis;
Female;
Glass;
Humans;
Iodine;
Middle Aged;
Neck;
Neoplasm Metastasis*;
Thyroglobulin;
Thyroid Gland*;
Thyroid Neoplasms*;
Thyroidectomy
- From:Korean Journal of Dermatology
2013;51(10):797-800
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cutaneous metastasis of papillary thyroid carcinoma is very rare and is a marker for wide dissemination. A 62-year-old woman presented with an asymptomatic, solitary, bean sized bluish nodule on the right anterior neck. She noticed the lesion 2 years ago and the nodule had been steadily enlarging. Five years ago, she underwent fine needle aspiration biopsy, right lobectomy, and total thyroidectomy and was diagnosed with papillary thyroid carcinoma. Since then, she has received radioactive iodine treatment three times and gone through whole body PET-CT scan twice, which revealed nonspecific findings. A biopsy specimen showed a well demarcated nodule consisting of many tumor cells with multiple follicular structures in the dermis. Tumor cells had ground glass nuclei, nuclear pseudoinclusions and nuclear grooves, and stained positive for thyroid transcription factor-1 and thyroglobulin. Herein, we report a case of cutaneous metastasis of papillary thyroid carcinoma suspected of iatrogenic cause.