A Case of Atrophoderma of Pasini and Pierini Associated with Borrelia burgdorferi Infection Successfully Treated with Oral Doxycycline.
- Author:
Yoonhee LEE
1
;
Yoonseok OH
;
Seok yong AHN
;
Hwa young PARK
;
Eung Ho CHOI
Author Information
- Publication Type:Case Report
- Keywords: Atrophoderma pasini pierini; Borrelia burgdorferi; Doxycycline
- MeSH: Adolescent; Adult; Antibodies; Atrophy; Borrelia; Borrelia burgdorferi; Depression; Dermis; Doxycycline; Female; Humans; Skin; Thorax; Young Adult
- From:Annals of Dermatology 2011;23(3):352-356
- CountryRepublic of Korea
- Language:English
- Abstract: Atrophoderma of Pasini and Pierini is a form of dermal atrophy that manifests as either single or multiple, sharply demarcated, hyperpigmented, non-indurated patches. These patches are marked by a slight depression of the skin, with an abrupt edge (i.e., the "cliff-drop" borders), usually located on the backs of adolescents or young adults. The pathophysiology of the disease is unknown, but some authors have suggested a role of Borrelia burgdorferi infection. A 35-year-old woman visited our department because of asymptomatic, hypopigmented, depressed patches on her chest and back lasting for three months. Laboratory evaluations were normal, except for positive serum antibodies to Borrelia burgdorferi. Histologic examination revealed a significantly decreased thickness of the dermis. The patient underwent treatment with oral doxycycline 200 mg/day for six weeks, after which the depth of depression was improved. Herein, we report a case of atrophoderma of Pasini and Pierini, associated with Borrelia burgdorferi infection, successfully treated with oral doxycycline.
