A Case of Generalized Pustular Psoriasis Improved with Isotretinoin.
- Author:
Jeong Joon OH
1
;
Jae Hong PARK
;
Soo Hong KIM
;
Dong Yoon LEE
;
Joo Heung LEE
;
Eil Soo LEE
Author Information
1. Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. eslee@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Generalized pustular psoriasis;
Isotretinoin
- MeSH:
Acitretin;
Adult;
Etretinate;
Female;
Humans;
Isotretinoin*;
Psoriasis*;
Skin
- From:Korean Journal of Dermatology
2003;41(12):1667-1669
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Generalized pustular psoriasis is a lethal variant of psoriasis characterized by the appearance of sterile pustules on psoriatic skin. Etretinate and acitretin are effective in pustular forms of psoriasis, including generalized pustular psoriasis. A major concern with the use of systemic retinoid is their high teratogenic potential. Since etretinate and acitretin are remetabolized into long-lived compounds, isotretinoin may be used to treat women of childbearing years with generalized pustular psoriasis. We report a case of generalized pustular psoriasis in a 28-year-old woman whose condition was improved with isotretinoin. Clinical improvement was noted with the administration of isotretinoin at the dose of 30mg/day.
