Comparison of CT-Guided Sclerotherapy with Using 95% Ethanol and 20% Hypertonic Saline for Managing Simple Renal Cyst.
- Author:
Hulusi EGILMEZ
1
;
Vedat GOK
;
Ibrahim OZTOPRAK
;
Mehmet ATALAR
;
Ali CETIN
;
Mubeccel ARSLAN
;
Yener GULTEKIN
;
Orhan SOLAK
Author Information
- Publication Type:Original Article ; Comparative Study ; Randomized Controlled Trial
- Keywords: Kidney, cyst; Kidney, interventional procedures; Sclerotherapy; Alcohol; Kidney, CT
- MeSH: Adult; Aged; Ethanol/administration & dosage/*therapeutic use; Female; Follow-Up Studies; Humans; Kidney/drug effects/radiography/ultrasonography; Kidney Diseases, Cystic/*drug therapy; Male; Middle Aged; Prospective Studies; Saline Solution, Hypertonic/administration & dosage; Sclerosing Solutions/administration & dosage/*therapeutic use; Sclerotherapy/adverse effects/*methods; Tomography, X-Ray Computed/*methods; Treatment Outcome
- From:Korean Journal of Radiology 2007;8(6):512-519
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: We wanted to compare the efficacies of 95% ethanol and 20% hypertonic saline (HS) sclerotherapies that were performed in a single session under CT guidance for the management of simple renal cysts. MATERIALS AND METHODS: A prospective series of 74 consecutive patients (average age: 57.6 +/- 8.1 years) with simple renal cysts were enrolled in this study. They were randomized into two groups and 95% ethanol or 20% HS, respectively, corresponding to 25% of the aspiration volume, was injected. Treatment success was determined six months later with follow-up clinical evaluation and performing ultrasonography. RESULTS: The sclerotherapy was accepted as technically successful without major complications in all except two patients who were excluded because of a communication between the simple renal cyst and the pelvicalyceal collecting system. Thirty-six patients in the ethanol group received sclerotherapy with 95% ethanol and 36 patients in the HS group underwent sclerotherapy with 20% HS. The complete regression ratio of the ethanol group was significantly higher (94% versus 72%, respectively) than that of the HS group. There was one patient with partial regression in each group. The failure ratio of the ethanol group was significantly lower (3% versus 25%, respectively) than that of the HS group. CONCLUSION: Ethanol sclerotherapy under CT guidance is a successful and safe procedure and it can be used for the treatment of simple renal cysts. Sclerotherapy with 95% ethanol is more effective than 20% HS sclerotherapy. Sclerotherapy with HS may be an option for patients preferring to undergo a less painful treatment procedure.
