Pure Immature Teratoma with Increase of Serum alpha-fetoprotein: A Case Report.
- Author:
Bohng Hee KIM
1
Author Information
1. Department of Pathology, Dankook University Hospital, Chonan 330-715, Korea. bohnghee@hanmail.net
- Publication Type:Case Report
- Keywords:
Teratoma;
alpha-fetoprotein;
Ovary
- MeSH:
alpha-Fetoproteins*;
Carcinoma, Embryonal;
Child;
Endodermal Sinus Tumor;
Female;
Humans;
Liver;
Neoplasms, Germ Cell and Embryonal;
Ovary;
Prognosis;
Respiratory Mucosa;
Teratoma*
- From:Korean Journal of Pathology
2007;41(1):63-65
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In the immature teratoma with increased serum alpha-fetoprotein (AFP), a complete pathologic examination is especially required because coexistence with other germ cell tumors is associated with a poor prognosis. If the case is proved to be a pure immature teratoma in spite of a thorough examination, the source of AFP should be found as an AFP-producing pure immature teratoma is not associated with a poor prognosis. In this case of a grade III-immature teratoma in an ovary of a 12-year old girl, serum AFP was increased. On pathologic examination, there was no evidence of a yolk sac tumor or embryonal carcinoma. On an AFP immunohistochemical stain, immature liver tissue, digestive and respiratory epitheliums were positive.
