Two Cases of Primary Osteolytic Intraosseous Meningioma of the Skull Metastasizing to Whole Skull and the Spine.
10.3340/jkns.2012.51.3.151
- Author:
Hyool KIM
1
;
Tae Young JUNG
;
In Young KIM
;
Jung Kil LEE
Author Information
1. Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital & Medical School, Gwangju, Korea. jung-ty@chonnam.ac.kr
- Publication Type:Case Report
- Keywords:
Intraosseous;
Meningioma;
Metastasis;
Osteolysis
- MeSH:
Aged;
Back Pain;
Biopsy;
Dura Mater;
Female;
Frontal Bone;
Humans;
Magnetic Resonance Spectroscopy;
Meningioma;
Neoplasm Metastasis;
Osteolysis;
Parietal Bone;
Scalp;
Skull;
Spine
- From:Journal of Korean Neurosurgical Society
2012;51(3):151-154
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report here two cases of primary intraosseous meningioma with aggressive behavior. A 68-year-old man presented with a one year history of a soft, enlarging mass in the right parietal region. Magnetic resonance image (MRI) revealed a 6 cm sized, heterogeneously-enhancing, bony expansile mass in the right parietal bone, and computed tomograph (CT) showed a bony, destructive lesion. The tumor, including the surrounding normal bone, was totally resected. Dural invasion was not apparent. Diagnosis was atypical meningioma, which extensively metastasized within the skull one year later. A 74-year-old woman presented with a 5-month history of a soft mass on the left frontal area. MRI revealed a 4 cm sized, multilobulated, strongly-enhancing lesion on the left frontal bone, and CT showed a destructive lesion. The mass was adhered tightly to the scalp and dura mater. The lesion was totally removed. Biopsy showed a papillary meningioma. The patient refused adjuvant radiation therapy and later underwent two reoperations for recurred lesions, at 19 and at 45 months postoperative. The patient experienced back pain 5 years later, and MRI showed an osteolytic lesion on the 11th thoracic vertebra. After her operation, a metastatic papillary meningioma was diagnosed. These osteolytic intraosseous meningiomas had atypical/malignant pathologies, which metastasized to whole skull and the spine.
